Thursday, May 4, 2017
Beta blocker intoxication
Hello!
This is a short blog on beta blocker
intoxication.
Beta blockers acting on beta receptors have wide range of actions and uses.
Most common complication of beta blocker overuse is Cardiovascular depression like hypotension and bradycardia, impaired atrioventricular functions.
Can we give adrenergic drugs to reverse this action?
No, we can't .
Prolong use of beta blockers leads to upregulation of the beta receptors. Beta Agonists will further aggravate the adrenergic actions.
Which may cause tachycardia even arrhythmias.
Even Atropine is inconsistent in reversing the side effects
So the alternative used is Glucagon -
It stimulates cAMP synthesis independently of beta adrenergic receptors.
It has positive ionotropic and chronotropic action, thus it reverses the cardiovascular depression without causing tachycardia or other adrenergic effects.
It can also be used in calcium channels blocker overuse.
Glucagon therapy still dont have enough evidence to prove its efficiency.
Hence Judicious use of drugs is must.
Stay awesome!
~Khush
Effects of cholinergics and anticholinergics on the bladder mnemonic
Cholinergics, bethanechol, diabetes mellitus, denervation and overflow incontinence.
Anticholinergics, oxybutynin, urge incontinence.
And mnemonics. Enjoy!
Risperidone mechanism of action mnemonic
Risperidone is a second-generation antipsychotic that has affinity for D2, 5-HT2A, alpha 1, alpha 2 and H1 receptors.
The mechanism of action of risperidone is not fully understood, current theories focus mainly on its ability to block D2 and 5-HT2A receptors.
Hard time remembering this? I've got a solution!
Wednesday, May 3, 2017
Initiation factors in eukaryotic translation mnemonic
Chaitanya Inge
Rubeola vs Rubella mnemonic
RubeOla - Ordinary measles ( kOplik spots on buccal mucosa are pathognomic )
RuBella ( German measles ) - Well, I remember Bella B. Felsenheimer, a German musician and drummer ( Foschheimer spots on the soft palate are characteristic ).
Thats all
- Jaskunwar Singh
Torres bodies mnemonic
Okay, to be honest this one is not quite a very good mnemonic but I like to remember Torres bodies in yellow fever by the footballer Fernando Torres wearing his club jersey in yellow color, even if he doesn't. Well, yeah, that's about it! :-p
-Sushrut Dongargaonkar
Tuesday, May 2, 2017
Diagnostic Enzymes in Myocardial Infarction
I am very thankful to IkaN for helping me with Troponin and CK-MB. :)
Thats all,
Drugs that prolong QT interval mnemonic
Here are drugs that can prolong QT interval and cause Torsades de Pointes! The mnemonic is TOOOOORSADES!
Cerebral ring enhancing lesions Mnemonic
Cerebral Ring enhancing lesions are a common finding in MRI based questions asked in the boards. ;)
The mnemonic to help you remember it is: Suppose there is a Dr Grams who is missing his wedding ring and is searching for it fervently. So if you're doing an MRI and you see a ring what should you do?
CAL DR GRAMS
C- Contusion
A- Abscess
L- Lymphoma
D- Demyelinating disease
R- Radiation necrosis
G- Glioblastoma
R- Resolving Haematoma
A- Abscess
M- Metastatic lesion
S- Subacute infarct
Here's a mnemonic submitted by Jaskunwar Singh. It includes Tuberculosis and toxoplasmosis!
CAL DR SMART
C - Contusions
A - Abscess
L - Lymphoma
D - Demyelinating diseases
R - Radiation necrosis
S - Subacute infarct
M - Malignancy / Metastatic lesions
A - AIDS
R - Resolving haematoma
T - Toxoplasmosis / TB
I assume that everybody knows about toxoplasmosis and tuberculosis so I didn't include them in my mnemonic. Use the mnemonic that suits you =)
That's all :)
-VM