Study group discussion: Fall of fever by crisis and fall of fever by lysis

Difference between fall of fever by crisis and fall of fever by lysis ?

In fall of fever by crisis, there's sudden decrease in temperature (Mostly due to treatment).

In fall of fever by lysis, reduction in temperature occurs gradually.

Typhoid fever falls by lysis.
(Step ladder pattern!)

Dengue fever falls by crisis.

Systemic sclerosis autoantibodies mnemonic

Today, I forgot which antibodies scleroderma is associated with T_T

Apparently, Qbanks don't write Scl-70 in their options. They like writing "Autoantibodies against topoisomearase I" and make my life difficult.

Anyway, here's my attempt to remember this next time. I don't know if it'll work. But hey, no harm trying?

Mauskopf facies

Hello!
Here's a fact I read today.

"Mauskopf" means "Mouse head" in German.

IkaN be a Khaleesi

Hello!
This post is from the authors diary.

Game of thrones fan, continue reading.

Someone sent me this which is pretty hilarious. I sent it to two of my friends, one added more to it and the other suggested I put it on the blog xD

Different types of skin lesions (as in rashes)

                          Hey guys, we started Internal Medicine Last week, so we were studying about different types of skin lesion as in rashes in Harrison’ Internal Medicine 19e. So I made little chart myself to memorize it. So I thought to share it with you all.

Polymyalgia rheumatica and giant cell arteritis mnemonic

Here's a mini post for the day!

What are the symptoms of Polymyalgia rheumatica? What is it associated with?

#AnswerTime: A patient with delusion

Here's the answer to a question we posted earlier: http://www.medicowesome.com/2016/08/quiztime-patient-with-delusion.html

Answer:

#QuizTime: A patient with delusion

#QuizTime
A 32 year old male patient came to the Psychiatry  OPD complaining  that his wife wanted to kill him. He was asked why he didn't report to the police , to which he said they were not ready to believe him.
He was suspected of having a delusion of persecution.

De Quervain syndrome notes

Intro:
Here's a short post on De Quervain syndrome :D

Correction of hyponatremia and hypernatremia mnemonic

Hello!

Never correct sodium too quickly.

If you correct hypernatremia too fast, it'll result in cerebral edema. Why?
When hypernatremia is corrected too rapidly, cerebral edema results because the relatively more hypertonic ICF accumulates water.

If you correct hyponatremia too fast, it'll result in central pontine myelinolysis (CPM) aka osmotic demyelination syndrome. Why?

Chronic hyponatremia is associated with the loss of osmotically active organic osmolytes (such as myoinositol, glutamate, and glutamine) from astrocytes, which provide protection against brain cell swelling.
However, organic osmolytes cannot be as quickly replaced when the brain volume begins to shrink in response to correction of the hyponatremia. As a result, brain volume can fall from a value that is initially somewhat above normal to one below normal with rapid correction of hyponatremia.
The mechanism by which a rapid fall in brain volume results in demyelination has not been established.

How do I remember this?

Central pontine myelinolysis* mnemonic

Here's another mnemonic:
From low to high, your pons will die (CPM)
From high to low, your brain will blow (Cerebral edema, herniation)

That's all!

-IkaN

Study group discussion: Widow makers artery

Does anyone know why left anterior descending artery is called widow's artery?

Approach to acid base disorders: Metabolic alkalosis notes

In suspected metabolic alkalosis, always check urinary chloride levels.

Metabolic alkalosis associated with a reduction in the ECV (Vomiting, diuretics):
There will be a stimulus for Na and Cl reabsorption to replenish extracellular volume.
Urinary Cl is very low ( < 25 meq/L).
Administration of NaCl and water leads to correction of the metabolic alkalosis.
Such causes of metabolic alkalosis are said to be saline responsive.

Approach to acid base disorders: Metabolic acidosis notes

Hello!

I made these notes while studying acid base disturbances. Now they might not make sense to someone who has never studied this topic before.. But for those who have read about it, this should be excellent for revision.

Calculation of anion gap:
ALWAYS calculate the anion gap first.
Anion gap = [Na+]  − ([Cl-] + [HCO3−])
Normal anion gap = 8 - 16 mEq / L

What causes renal bruit?

Narrowing of the renal artery (Renal artery stenosis) causes renal bruit.

Hexagonal crystals in cystinuria mnemonic

Hexagonal crystals are seen in cystinuria.

Envelope shaped crystals in urine: Calcium oxalate mnemonic

Heyyyyyy!

X in oXalate looks like an envelop to me :D

Drugs causing crystal induced AKI mnemonic

Hello!

So today I was reading about acyclovir and crystal induced acute kidney injury.

Acyclovir is rapidly excreted in the urine (being both filtered and secreted) and has a relatively low solubility. Intravenous (IV) therapy may lead to the deposition of acyclovir crystals in the tubules if the patient is volume depleted. This results in intratubular obstruction and foci of interstitial inflammation.

Secondary focal segmental glomerulosclerosis mnemonic

How to remember diseases associated with focal segmental glomerulosclerosis - Remember the letter H!

Hodgkins lymphoma and minimal change disease

Fact for the day: Hodgkins lymphoma is associated with minimal change disease.

Complications of nephrotic syndrome

Complications of nephrotic syndrome:

Infection with encapsulated bacteria, varicella (Vaccinate before or during treatment with high dose steroids)

Thromboembolism due to decreased antithrombin III (Prophylactic anticoagulation is not recommended unless patient has had a thromboembolic event, albumin < 2 g/dL, fibrinogen > 6 g/L, antithrombin < 70%)

Hypovolemia, anascara, renal insufficiency.

Increased risk of early atherosclerosis due to hyperlipidemia.

Multiple Endocrine Neoplasia

MEN are autosomal dominant syndromes.

They are classified as-

1. MEN 1 ( Wermer syndrome)
Pituitary, pancreas & Parathyroid adenomas.

2. MEN 2
a) 2A (Sipple syndrome)
Hyperparathyroidism, medullary carcinoma of the thyroid and pheochromocytoma.
b) 2B
Medullary carcinoma of the thyroid, pheochromocytoma, and mucosal ganglioneuromatosis.

Related post: MEN syndrome mnemonic