Cyber knife

This new technique in radiotherapy is revolutionising the world of treatment in oncology. The technique is largely unheard and my intention of writing the post is to share it with a maximum number of people.

Invented by John R Adler, Peter and Russell Schönberg in 1990, 'CK' is about targetting radiation with a high accuracy to neoplastic tissues.

A linear accelerator of 6MV delivers X ray radiation of 6-800cGy while a  robotic arm maneuvers the 'linac' around the body of the patient so that most of the neoplastic cells are irradiated. An accuracy of 0.5 mm is maintained during the process.

For ensuring such level of accuracy, tissue tracking is needed. There are different methods of tracking for bones, lungs and viscera. For soft tissues like pancreas, gold fiducials(hair like implants) are inserted so that the movement of the tissues as the patient breathes can be identified accurately.

About 1-5 sessions are needed depending upon the pathology. There's no anaesthesia and long treatment hours involved, unlike surgery. Plus, the procedure is significantly cheaper than say, Whipple's pancreaticoduodenectomy!

-Thats all!

Causes of Acute Pancreatitis

Hi guys,

I have an exam soon and I was struggling with this, so, I made this up!

To remember causes of Acute Pancreatitis, you need to think of none other than your nursery school days! :P

So, here we go- ABCDEFGHI, (oh wait did I just say "HI" :P)

Now going a little off track, but, when I was small I used to do a lot of gardening, so I remember rest of the causes as Me POT.

Alcohol ingestion  (acute or chronic)
Biliary calculus
Connective tissue diseases- SLE, TTP,  PAN
Drugs- diuretics- frusemide, thiazide. (Others are anti retroviral drugs, sulphomamides, tetracycline, tamoxifen, etc)
Endoscopic procedures
Familial/ Genetic
Hereditary Pancreatitis/ Hyperparathyroidism/ hypercalcemia/ Hypertrigylceridemia
Infections- viral

Metabolic conditions - renal failure,
Penetrating Peptic Ulcer
OPC poisoning
Trauma to abdomen

Phew, a long list. Isn't it?

Hope it helps!!
That's it!

-Rippie

Head transplant

Recently during surfing on net ,i came across very interesting topic of surgery -Head transplant ,would like to share with you all people
World's 1st attempt to transplant a human head was launched in year 2015 at a surgical conference in united states.
Procedure was 1st put forward by Sergio canavero -an Italian neurosurgeon.
The actual procedure will be as followed :

Two teams will work in concert making deep incisions on patient's neck exposing vital arteries, veins and nerves ,next step is the most crucial step of cutting spinal cord using $200,000 diamond nanoblade !.
Head is than moved on to donors body and spinal cord can be fused together using polyethylene glycol to encourage the fat in cell membrane to mesh out once the neck is transplanted
and then patient would then be placed into a coma for about a month to prevent movement and to allow healing procedure
while implanted electrodes provide regular electrical stimulation to spinal cord finally when patients wakes up from coma he will be able to see his face and speak !!!! But will need a physiotherapy for 1 year to begin walking .
Dr sergio canavero said that surgery would be ready in 2017 probably .
A computer scientist Spiridonov with Werdnig-Hoffman disease has volunteered to offer his head to study as he is suffering from incurable spinal muscular atrophy and has decided to give one final shot to have a new body !

~Ojas

Tongue depressor and bipod stand

Boyle- davis tongue depressor

This instrument is used to lower down the tongue and hold it while the Davis mouth gag serves to hold the mouth open during tonsillectomy and other oral procedures. it comes in various sizes and used depending upon the age of patient.

The mouth gag is held in position by using the Draffin bipod stand which consists of two rods.

Thats all
- Jaskunwar Singh

Tonsil holding forceps

Denis Browne's tonsil holding forceps

Used in tonsillectomy to grasp the tonsils and pull medially. (dissection method)

The shaft is bent at an angle towards the handle. Ends of this instrument are cup- shaped with holes.



Thats all
- Jaskunwar Singh

Killian's nasal speculum

Killian's long bladed self- retaining nasal speculum

Used in Submucous resection (SMR) and septoplasty procedures.

It helps keep mucoperichondrial flaps away to make space for proper access and vision to the interior of nose and perform surgery efficiently.

IMPORTANT: In septoplasty, the flap is raised only on one side while in SMR, both sides flaps are raised. So due to cosmetic reasons and high risk of septal complications, septoplasty is preferred over the submucous resection.


Thats all
- Jaskunwar Singh

Direct Laryngoscope

As the name suggests, this instrument is used for direct visualization of larynx and hypopharynx. 

Diamond blackfan anemia notes and mnemonic

Diamond blackfan anemia

It is congenital pure red cell aplasia.

A 7 year old with hyperextensible joints

A 7 year old boy is brought to you. He is intellectually disabled. On examination, you notice hyperextensible joints. Large hands, large feet, protruding ears, elongated face are also seen. The patients testes are large in size compared to his age. Diagnosis?

Marfans syndrome
Ehler Danlos syndrome
Fragile X syndrome
Friedreichs Ataxia
Homocystinuria

Answer below
.
.
.
.
.
It's Fragile X syndrome. Why isn't it's Marfans? Because Marfans has normal IQ.

Here are my notes + mnemonic for Fragile X syndrome.

Did you know?
Fragile X is the most common cause of inherited mental retardation.
It was the first trinucleotide repeat disorder to be recognized.

That's all!
-IkaN

Walsham's forceps

Walsham's forceps

Uses: to correct lateral deviation of fractured nose and disimpaction

and repositioning of bony fragments.

Most students get confused between Walsham's forceps and Asch's forceps. The difference is in the structure of the instruments itself.

Walsham's forceps: paired instrument used for reduction of nasal bone fractures. One nasal blade is placed externally while the other blade goes into the nose and supports the nasal bone.
Also, the blades are not elevated in walsham's forceps as in the case of asch's.

Asch's forceps: unpaired instrument used for reduction of nasal septum and vomer fractures. It is used along with Walsham's forceps for the reduction procedures. The blades are elevated. (ASCh = Ascending)


Thats all
- Jaskunwar Singh

Trousseau's tracheal dilator

Trousseau's tracheal dilator

Used to widen the tracheal incision to aid in the insertion of

 tracheostomy tube.

Remember: It is curved at its ends so that it doesn't block the field of vision of the surgeon while making the incision and insertion of the tube.

Thats all
- Jaskunwar Singh

Toynbee's ear speculum

Toynbee's ear speculum

Uses: Examination of external ear and tympanic membrane

In operative procedures like myringoplasty, myringotomy.
Removal of wax, foreign body, otomycosis, ear discharge.

Different sizes for patients according to age.

Thats all
- Jaskunwar Singh

Tonsil artery forceps

This instrument is of two types: straight and curved.

Straight forceps (Birkitt's tonsil artery forceps) used to catch the bleeding point. (in tonsillar fossa) following tonsillectomy.

Birkitt's first tonsillar artery forceps

Wilson's second artery forceps

Curved forceps used as replacement forceps before tying a ligature to the bleeding points following tonsillectomy. (also called Second tonsillar artery forceps)


Thats all
- Jaskunwar Singh

Asch's forceps

Asch's septum forceps

Used for reducing procedures in cases of nasal septum fractures. (Reduction Rhinoplasty) 

The septum is grasped with the blades of this instrument and straightened to make proper alignment.

The blades are elevated. Remember ASCh- Ascending.

The instrument is often confused with Walsham's fracture. Both are used in reduction procedures of fractures of nasal septum.
To know about differentiating features, click here.

Thats all
- Jaskunwar Singh

Thudicum's nasal speculum

Used to examine external nose.

Light is focused at different sites to examine antero- inferior part of nasal septum, roof, floor, and lateral wall by tilting patient's head in various directions.

There's a specific technique to hold this instrument during examination of the patient. Its really simple but if you don't practice to hold it, you will forget it for sure.
 Keep your ring finger beneath one arm of the speculum and index finger in between the two arms. Press the other arm with middle finger such that the two lower ends meet. 

Here's the picture of the right way to hold it.-

Luc's forceps

Lets start with instruments used in surgical procedures of Otorhinolaryngology..

Firstly, lets talk about Luc's forceps.

This instrument has a fenestrated tip with sharp blades to hold

and grasp a tissue and cut it. So basically it is used for cutting.

Uses:

1. As the name suggests, it is used in Caldwell- Luc's operation (Anterior antrostomy) for removing antral mucosa. 

2. Submucosal Resection of nasal septum. (to remove bone or cartilage from the septum required for a graft)

3. Polypectomy  

4. Turbinectomy

Thats all

- Jaskunwar Singh

A tip for confusing things

many of us have this tendency and inner hunger to know everything, but not all of us are prodigies now are we?

hence a typical example.

types of thyroplasty

type1- medialization of cord

type2- lateralization

type3- shortening

type4- lengthening

no many how many times i have read it, i am bound to get confused. i will remember that type 1 and type 2 had to do with changing the position of the cord from midline, but i am totally going to forget whether medialization was first or not. 

The examiners exploit this very weakness. some sadist i tell you! 

anyways not always will you be able to get your hands on mnemonics that will save your neck..and yes sometimes it is even really tough to remember the mnemonics themselves during exams -_-

my tip is 

just remember

type1- medialization

type3- shortening

hell with everything else..this attitude will save your neck more than you can imagine. use this with eveything confusing. 

just dont give your brain the chance to be confused..read and have a visual image of only the very core of the answer. and trust yourself that when push comes to shove you will be able to answer the question correctly 

-sakkan

Primary Health Care

Hey Awesomites

Today its a short post ( a mnemonic actually ;p )  on the principles and elements of primary health care. (I was asked in SPM viva a few days back. ;p )
As a rule, always find a mnemonic in the name itself, I took care of it and made it in the easiest way possible. So here it is ..

C- Community participation
A- Approach (multi- sectorial)
R- Right technology (appropriate)
E- Equitable distribution of health services.

Elements of primary health care: MI NEEDS
- MCH and family planning
- Immunization
- Nutrition
- Education
- Endemic and common diseases
- Drugs provision
- Sanitation.

Thats all
Happy Medicowesome :)

- Jaskunwar Singh

Caput v/s Cephalhematoma - Ways to remember.

Though simple, takes time in the exam if confused.

So here's a way to save the time meanwhile being sure of the answer for the topic.

Langerhans cell histiocytosis notes and mnemonic

Hey!

I'm clearly doing a lot of notes + mnemonic posts. Here's another one on Langerhans cell histiocytosis!

Langerhans lingers
L - Lytic lesion of bones
I - Diabetes Insipidus
N - Nil
G - Eosinophilic Granulomas
E - Exophthalmos
R - Rrrrr.... :P
S - Skin rash

From study group:

Any mnemonic for Hand Schuller Christian disease?

Mnemonic by IkaN: Hands LIE
Lytic bone lesions
Insipidus (Diabetes Insipidus)
Exophthalmos

Mnemonic by Dev: CDE
Calavarial skull defect
Diabetes insipidus
Exophthalmos

Disclaimer: It's a morbid mnemonic. If you are sensitive and religious, don't read it.
Mnemonic by Vinayak: Jesus CHRIST was killed by hammering nails into his HAND, he DIed, his hands' bone got LYSED and we celebrate EXmas:
For calvarial skull defects, you know, wood was also hammered into his head. DI is diabetes insipidus. EX is exophthalmos.

That's all!
-IkaN

Study group discussion: Skeletal resistance to PTH in CRF

Hi guys! So the question that was asked in the study group is- Why is there skeletal resistance to PTH in Chronic Kidney Disease?

Answer-

Skeletal Resistance to PTH has a multifaceted pathogenesis; the most imp factor being uraemia which screws with the PTH receptor's intracellular G-protein signaling mechanism in the Osteoblasts.

Dialysis in these patients increase the levels of Osteoprotegerin, which is a decoy molecule antagonizing the action of RANKL in promoting osteoclastogenesis; further intereference with the action of PTH.

Hyperphosphatemia and Hypocalcemia in CKD patients cause excessive release of PTH which leads to downregulation of its receptors on osteoblasts. 

Decreased levels of calcitriol screws in a special way, it makes the parathyroid gland think that the normal calcium level range is above the actual normal value, making the gland work overtime. For this we use calcimimetics like cinacalcet to decrease the set point back to the real normal value. And also without Calcitriol to assist, PTH's job becomes a lot more difficult. 

Earlier the most common CKD-related osteodystrophy was osteitis fibrosa cystica which was due to very high PTH levels causing pathologically increased bone turnover.

But now since we have developed drugs to tackle increased PTH levels, Adynamic Bone Disease has become the most common osteodystrophy because in the body of a CKD patient, it is already very difficult for PTH to carry out its function and if we are pharmacologically decreasing its values, we are ensuring that it works negligibly. 

That's enough Nephrology for one day! :)

  

-VM