Wednesday, May 30, 2018

MCQ mnemonics series: Mnemonic for a condition causing lower abdominal pain

A 60-year-old male is admitted with a two day history of lower abdominal pain and marked vomiting. On examination he has abdominal swelling, guarding and numerous audible bowel sounds. What is the diagnosis?
1) Gallstone ileus
2) Ischaemic colitis
3) Large bowel obstruction
4) Sigmoid volvulus

Answer given below:

Facebook: ANS and dilated pupil.

So, this post is regarding answer of our recent pharmacology question posted on facebook medicowesome group. If you still are not following it, please follow for latest updates and interesting questions.

Q) What is the probable diagnosis in a patient with a dilated pupil not responsive in 1% pilocarpine? (AIIMS 2011 Nov)

1) Diabetic 3rd nerve palsy.
2) Adie's tonic pupil.
3) Uncal herniation.
4) Pharmacological block.

Answer is option 4- Pharmacological block.

Let's start with the basics of the ANS to understand the question.

First, imagine an eye with simplest of the structures.
A central area called as pupil. Surrounded by group of muscles called as "constrictor pupillae muscles" which obviously helps in constriction (miosis) of the pupil as their name suggests. They are  further surrounded by "radial muscles" which causes dilation (and mydriasis) of the eye.

Now, each of these muscles will have receptors on them. Receptors need to be stimulated for their respective actions, right? - Yes!
Now, remember - M3 receptors are present on constrictor muscles and Alpha-1 receptors are present on radial muscles.

Now, you must be thinking why I am goofing around with such simple basic concepts?!
Hold on, question may contain confusing options but you already know the answer. Atleast now you do know!
(Read question again and come back!)

Pilocarpine is selective M3 agonist. Stimulation of M3 receptors will lead to miosis.

In pharmacological block, drugs like atropine block the muscarinic receptors present on the pupil. As, the receptors cannot work, pilocarpine cannot produce miosis.

( You really don't need to know all the things to answer MCQs. Sometimes basics are enough!)

Now, let us know more about other options.

1) Diabetic 3rd nerve palsy: Occulomotor motor nerve supplies constrictor puplillae So, palsy of 3rd nerve will cause mydriasis but does it cause any damage to receptors? - No.
So, pilocarpine will respond and thus miosis will occur!

2) Adie's tonic pupil: It manifests as denervation supersenstiviy. Normal pupil responds to 1% pilocarpine but not to dilated solution like 0.05-0.1%. However, in Adie's pupil due to supersenstiviy of receptors, even this diluted solution may results in constriction.

3) Uncal herniation: Pressure on 3rd nerve causes pupil dilation but again it will respond to pilocarpine as receptors are intact.

Some important MCQ points related to above information.
1) Echothiophate is also M3 agonists. It is an anti-glaucomic drug which acts by promoting drainage of fluid via schlemm's canal.
Adverse effect: Causes cataract.

2) Adrenergic drugs causes mydriasis (Stimulation of Alpha-1 receptors) and Anticholinergic drugs (Inhibiting M3 receptors) causes mydriasis and cycloplegia.

Monday, May 28, 2018

Tips to get interviews in top-tier residency programs

Who didn’t dream about starting his residency in a great famous program? What is your dream program? Is it Harvard? Yale? John Hopkins? Stanford?......and the list goes on..

It is hard but it is not impossible. Besides having nice USMLE scores, here are some points that make your application stands out:

1- Research
Doing a research in big institutes may help in getting a call from these places. While doing your research, you will be able to meet new people, some of them may know a person who is related to the residency selection process. At the same time, you are showing your commitment, social skills and your willingness to be a part of the team.
Another point to consider is having publications in international journals with a high impact factor. This includes but is not limited to JAMA, The Lancet, Nature, Cell. Whether you worked in institutes in the US to have these publications or you were involved in an international research that was eventually published in these journals, having such accomplishments is a great addition to your application.

2- MPH and/or PhD
Having a Masters degree - especially if done in the US - can be a big plus for some university programs. You may do masters in biostatistics,epidemiology and many others. It may be costly and lengthy (a year or two) but it's worth it.

3- Preliminary (transitional) year
Doing a preliminary year in some high-tier residency programs may be your winning ticket to enter that program. You may match in the same program or apply to and get interviewed by another amazing program since you will now have a 1 year of fully accredited USCE (United States Clinical Experience) in addition to the experience and knowledge that you gain.

4- Contacts
It is amazing how social life shapes us as humans. The importance of having contacts or making new ones during your research, MPH or preliminary year can’t be overemphasized. Programs prefer a person who they already know and whom they are sure they can work with.
Consider attending conferences in your field too, Pediatrics, Internal Medicine...etc.

5- Exceptional Academic Record
Famous institutes like applicants who are bright, smart and committed. An “excellent “academic record helps to prove this.

6- LUCK
Believe it or not, occasionally, luck plays a role here. Be outgoing and interact nicely with as many people as you can. Being in the right time at the right place is what you need sometimes!

Finally, for all AMGs and IMGs, always remember that the journey of a thousand miles begins with a single step. Start now and chase your dreams :)

-Murad

Complications of massive blood transfusion


Hii everyone! 

Massive blood transfusion is defined as

Complications from massive transfusion include :
1) Hypothermia
2) Hypocalcemia - because citrate present in transfused blood is a calcium chelator, it decreases the available calcium.
3) Acidosis - as citrate is acidic in nature.
4) Hyperkalemia - as Hydrogen ions are present in excess due to acidosis, it is compensated by H+ loss in urine and K+ is regained back into blood. So this causes hyperkalemia.
5) Hypokalemia - in stored blood, the Na+-K+ pump is less functioning,  so there is decrease in intracellular K+ in stored blood.  But after blood transfusion, the Na+ K+  pump again starts functioning and increases intracellular K+, this leads to decrease in the available K+ outside the cell causing hypokalemia.
6) Dilutional coagulopathy - massive blood transfusion leads to dilution of clotting factors . It later manifests as DIC-like leading to multiorgan failure and death.

Thanks for reading.

Madhuri.

Complications of blood transfusion

Hii everyone!
This post is about the complications from a single blood transfusion.

1) The most common complication is febrile nonhemolytic tranfusion reaction(FNHTR). -- this occurs due to anti-HLA antibodies in the recipient which kills WBCs leading to release of interleukins and cytokines which are pyrogens. So the treatment is antipyretics.
2) Urticaria - it is due to IgE antibodies in plasma. So we give antihistamines to control it.
3) Hemolytic transfusion reaction - due to antibodies against RBCs. This is rare.  It may occasionally occur due to clinical errors in pretranfusion tests.
4) Infections - bacterial infection due to faulty storage, hepatitis, HIV, malaria.
5) Air embolism
6) Thrombophlebitis
7) Transfusion- related acute lung injury - usually occurs within 6 hrs after transfusion.

Hope this helps.

Madhuri

MCQ mnemonics series: Genital tuberculosis most common site

#Obs_Gyn
Question:
Most common site of genital tuberculosis is?
(A) Fallopian tubes
(B) Uterus
(C) Ovary
(D) Fimbriae
________
Answer:

MCQ mnemonics series: Fusion inhibitors

#Pharmacology
# Antiretroviral drugs
Question
-
*Fusion inhibitor approved for use in HIV is*
a. Enfuvirtide
b. Atazanavir
c. Cobicistat
d. Rilpivirine
-
Answer:

MCQ mnemonics series: Naturally occurring anticancer drugs

#Pharmacology
#Anticancer Drug

Question
-
*All of the following are naturally occurring anticancer drugs except*
a. Irinotecan 
b. Paclitaxel
c. Etoposide
d. Chlorambucil
-
Answer

MCQ mnemonics series by Dr. Shubham Patidar

Hello Awesomites! :D

I am starting a new series for post graduate medical entrance examination. I'll be solving frequently asked confusing difficult MCQ by simple tricks, tips and mnemonics.

In every post MCQ along with authentic answer and mnemonic will be given!

Friday, May 25, 2018

Hematology Diagrams

Hello Awesomites! :D

I made these diagrams during my exams.
I kept in mind the details of cells.
Hope it will help.



-Upasana Y. :)

Thursday, May 24, 2018

Referred Pain

The pain sensation produced in some parts of the body is felt in other structures away from the place of development. This is called referred pain According to dermatome rule,
  • Pain is referred (transferred) to a structure.
  • This structure is developed from the same Dermatome from which pain producing structure is developed.
I know! It’s confusing *_*
Let me make it easy for you, There is a pain in your heart and this pain is transferred to your left arm.
How is this happening •_• This is because the heart and inner aspect of the left arm is developed from the same dermatome. Now, you must be thinking, what about other areas of the body!
  1. Pain in testis is referred to the abdomen.
  2. Pain in the ovary is referred to the umbilicus.
  3. Pain in the diaphragm is referred to the right shoulder.
  4. Renal pain is referred to loin.
Thought question: Do you know about any other areas? Comment me with your answers! 
I wonder, can acidity cause referred pain?

- Written by Anisha Valli

Wednesday, May 23, 2018

Time management tips for USMLE exams

The USMLE exams are really long and tiring but they are like parts of a big puzzle and each part does play an important role in the journey to become a doctor in the US.

This post will focus on some time management and test-taking skills that are helpful to each test-taker. I hope you enjoy reading

Before your exam:

1- It is advisable to do a simulation of the exam. Do 7 or 8 uworld blocks- with breaks in between - or 2 consecutive NBMEs or UWSAs. This way, you ll be familiar when you start to lose your concentration or feel hungry and when you will need a longer break between the blocks.

2- This is optional, but for some people, doing the practice test in the prometric greatly reduces the tension of the exam day. If you are very tensed, schedule a practice test in your prometric and live the experience. This is also considered a test drive and by doing this, you ll know exactly where the prometric is :)

The night before the exam:

1- Sleep well. You need each synapse in your brain to work perfectly :D your memory and logic will be tested tomorrow. Your brain should be ready for that.

2- Try your best to sleep without taking any meds, if u have to, make sure that this time is not the first time you try them.

Exam morning:

1- Arrive early to the prometric, 30-40 mins earlier than your exam starting time. You'll sign some papers and pass a simple security check.

2- Wear comfortable clothes with less pockets and shorter sleeves. You ll be asked to show your pockets and roll your sleeves each time you go out for a break and each time you back into the exam hall.

Blocks and breaks:

1- Skip the tutorial
By doing this, you ll have a complete one hour break instead of a 45 minutes one. The tutorial will show you the software which is a replica of Uworldso save your time and use these 15 precious minutes.

2-Pre-schedule breaks according to the previous simulation
Enter the exam with a plan in mind about using your breaks. Will you take a small break after each block? Will you do 3 blocks with breaks then 2 without? Choose what best suits you based on what you felt during the simulation that you did. For example, you might have felt hungry after your 3rd block, so you may need a longer break in the real exam after your 3rd block.

2- Eating, drinking and using the restroom
Use your breaks wisely. Eat small things/snacks in breaks to avoid hypoglycemia during the exam and eat a small sandwich/breakfast before the exam to have some energy to start.
Don’t forget to "visit" the restroom in your breaks. You are not allowed to go to the restroom during a block, if you urgently need to do that, this will be labelled as “an irregular behavior” and it will be reported to ECFMG.

3- Staying in the exam hall
You don’t have to leave the hall during your break. If you wanna take a fast 5 minutes break, you can simply stay where you are, close your eyes, relax your mind and continue your exam when you feel ready

While solving blocks:

1- Reading the question/the last line first
 Always read the last line first in all USMLE exams, some questions are answered only by reading this last line! Especially in pharmacology questions, you may have a question stem which is 12 lines long then you ll read: What is the mechanism of action of …..? This will help you to save some valuable seconds.
As a rule, read last line first then go back and read the question normally.

2- Highlight any abnormalities
When you read a question, highlight the age,sex and where the patient was admitted; ER, outpatient. Also highlight any abnormality like hemodynamic instability….chest pain...etc.
Your eyes will focus on these findings and will try to associate them to reach a diagnosis.

3- Omit distractors
With time, this becomes a skill in the USMLE world, you realize that many sentences are just fillers to distract you. For example, a myocardial infarction in a 70-year old male, a person who smokes only occasionally or who drinks on weekends.

4- Resist the urge to re-re-read, simply mark and go on
Read the question and apply the hints mentioned above. If you don’t know the answer yet, read the highlighted parts again, if you still don’t know the answer or you are not 100% sure of it, pick the one you feel it is the right one, mark the question and move to the next question. You may get back to this question only when you finish answering all other questions.

5- Leave abstracts and drug ads till the end
This applies for Step 2 CK and Step 3 exams. Abstracts and drug ads are very lengthy and they may take a lot of time in addition to the fact that many statistically insignificant data is thrown here and there. When you see an abstract or a drug ad, choose any answer then move on and go back only when you finish all other questions. It’s illogical to spend 10 minutes on 2 drug ad questions and miss 7 questions at the end of the block!

6- Don’t leave unanswered questions
Even if you don’t have any clue about a question when you read it, choose an answer, mark it and go on. Having a 20% possibility to answer the question right (supposing a question has 5 choices) is better than having nothing. This will also save some much needed seconds, because if you read a hard question then skip answering it, after reading another 20 questions, you' ll have to re-read the hard one.

In general, don’t change your first answer, your first hunch is most probably the right one. Change your answer only if you are sure that the one that you chose is wrong.

Test taking skills are very important and play a vital role in your journey

Good luck to everyone :) USMLE exams are tough but manageable, just tell yourself: I WILL DO IT :)


And that’s it :)
Murad

Tuesday, May 22, 2018

Interglobular Dentin


  • Sometimes mineralisation of Dentin begins in small globular areas that fail to fuse into the homogeneous mass. 
  • It results in Zones of Hypomineralisation between globules. 
  • Most commonly found in Circumpulpal Dentin which is present below the Mantle Dentin. 


In other words, in poorly formed teeth, due to deficiency of vitamin D or exposure to fluoride, it leads to defect in mineralization i.e. loss of globular dentin.

Note: Defect is not because of improper matrix formation.

Thought Question: Dentinal tubules pass uninterruptedly through Globular Dentin. Why? Comment your answers!

- Written by Anisha Valli

Saturday, May 19, 2018

Leech therapy for venous congestion

Today, I came to know that leeches are a well-recognized treatment for congested tissue :O

When this image was sent to me, I thought it was an infestation. After reading about it though, it was clarified that the leech was put deliberately by the plastic surgeons to treat venous congestion (hirudotherapy). 

Authors' diary: Life support


Wednesday, May 16, 2018

AML and ALL differentiating features.


Hello awesomeites !

Today let us find out the difference between AML and ALL on the basis of cell morphology, cytochemistry and immunophenotyping.

So, Acute Leukemia is the presence of blasts >=20% either in peripheral blood or bone marrow.

Myeloblasts in AML and Lymphoblasts in ALL are the two main types

Cell morphology:

Myeloblasts:  The characteristic feature is the presence of Auer rods with moderate amount of cytoplasm and cytoplasmic granules and multiple nucleoli
Lymphoblasts:  They have a scanty cytoplasm no granules and nucleoli are not present
Many a times differentiating the two on morphological basis isn’t feasible. So we take the help of cytochemistry.

Cytochemistry:

Myeloblasts:  are myeloperoxidase(MPO) and Sudan black B (SBB) positive
                         Monoblasts which are a part of the myeloid lineage are nonspecific esterase (NSE) positive
Lymphoblasts:  are periodic acid Schiff (PAS) positive
MPO stains the enzyme within the azurophilic granules and is the most specific while SBB stains the lipid membrane of the azurophilic granules and is most sensitive for myeloid differentiation .
Even after this if we aren’t able to differentiate then we take the help of immunophenotyping

 
Immunophenotyping:

It is performed by flow cytometry.
The sample either bone marrow or peripheral blood is stained with antibodies and the cells are allowed to fall freely in a single file across a beam of laser (this is the over simplified version of it :P).
The laser used is Blue laser of wavelength 488nm. When the laser beam hits the cells some of it gets scattered to the sides and is known as the side scatter which is a measure if the granularity of the cells. While the rest of the beams travel in the same line without deviation and is called as the forward scatter and is a measure of the size of the cells.
Neutrophils are the cells with the highest side scatter.
Staining of the cells with antibodies helps in subtyping acute leukemias on the basis of CD markers.

Here is a list of CD markers on varies cells of myeloid and lymphoid lineage

B cell markers:
CD19: present on all B cells
CD10: immature B cells
CD20: mature B cells

T cell markers:
CD3: present on all T cells
CD4 CD8 CD2 CD5 CD7 are some of the other markers present on various T cells

Myeloid markers: CD13 CD33 CD117

Stem cell markers: CD34

Monocyte markers: CD14 CD64

NK cell markers: CD16 CD56
CD45 is present on all leucocytes a.k.a pan leucocyte marker 


That’s all for now, hope this helps in better understanding of AML and ALL!
Keep calm and keep studying!
Stay awesome!
-          Ashish G. Gokhale

Tuesday, May 15, 2018

AFASS criteria

Hello Awesomites ! :D

AFASS CRIETRIA is used to decide whether a HIV positive mother can breast feed or not provided that she has not started top feed yet.
(Why? Once the mother started to top feed the child, this criteria is not used. HIV positive mother in such case should continue top feed. Because mixed kind of feed is more dangerous than top feed alone)

Acceptable: The mother perceives no problem in replacement feeding. Potential problems may be cultural, social, or due to fear of stigma and discrimination.

Feasible: The mother (or family) has adequate time, knowledge, skills, resources and support to correctly mix formula or milk and feed the infant up to 12 times in 24 hours.

Affordable: The mother and family, with community or health system support if necessary, can pay the cost of replacement feeding without harming the health or nutrition status of the family.

Sustainable: Availability of a continuous supply of all ingredients needed for safe replacement feeding for up to one year of age or longer.

Safe: Replacement foods are correctly and hygienically prepared and stored, and fed preferably by cup.

Source: http://motherchildnutrition.org/info/afass-principles.html (Click to know what all questions are asked)

-Upasana Y.:)

Inguinal lymph nodes

Hello Awesomites! :)
Long time. Happy to be back. :D

Today we will study Inguinal Lymph nodes along with its clinical significance.

You know fascia lata is present in our lower limbs.

The Lymph nodes lying above it is called as superficial inguinal Lymph nodes.
The Lymph nodes lying beneath it is called as deep inguinal Lymph nodes.

The superficial Lymph nodes are further divided into horizontal and vertical groups.
The deep lymph nodes are deep to fascia lata and 1-2 nodes can be found in femoral canal. This nodes in the femoral canal are called as deep inguinal Lymph node of Rosenmuller or of Cloquet. This drains glans penis and clitoris.

Through the umbilicus is taken a watershed line of Lymphatic drainage of anterior abdominal wall.
The anterior abdominal wall below the umbilicus drains in the superficial inguinal lymph nodes.
Entire perineum except glans penis and glans clitoris are drained by superficial lymph nodes.
Most of the lower limb is drained by superficial inguinal lymph nodes except the territory of short saphenous vein (This part of lower limb is drained by popliteal group of lymph nodes).

Some part of Uterus and uterine tubes are also drained by superficial inguinal lymph nodes.
Anal canal below pectinate line also drains in superficial inguinal lymph nodes.

Superficial Inguinal lymph node drain lymph from the
1.     gluteal region,
2.      inferior anterior abdominal wall,
3.      perineum
4.     superficial lower limbs
5.     Anal canal below pectinate line
Deep Inguinal Lymph node drains
1.     deep lymphatics of the distal lower extremity
2.      perineum (e.g. glans penis / clitoris),

CLINICAL SIGNIFICANCE:

In sexually transmitted diseases, you will find enlargement of this lymph nodes.
Inguinal lymph nodes are the frequent sites of metastasis for malignant lymphoma, squamous cell carcinoma of anal canal, vulva and penis, malignant melanoma and squamous cell carcinoma of skin over lower extremities or trunk. 

-Upasana Y. :)


Sunday, May 13, 2018

Allergic Broncho-Pulmonary Aspergillosis (ABPA) treatment mnemonic

To remember that Allergic Broncho-Pulmonary Aspergillosis is treated by corticosteroids mainly and not anti-fungals although Aspergillus is a fungus, just write:

Allergic Broncho- Pulmonary Aspergillosis ==> as => Allergic BronC-Orticosteroids Pulmonary Aspergillosis

and that's it :)

-Murad

Sunday, May 6, 2018

Query on Step 2 CS deadline & match timeline

I read this link and I'm confused, it says:

To participate in the National Resident Matching Program® (NRMP®) Main Residency Match®, international medical students/graduates must have passed all exams required for ECFMG Certification. If you plan to participate in the 2019 Match (in March 2019) and still need to pass Step 2 Clinical Skills (CS), you should register now to take the examination.

To help ensure that your result will be available in time to participate in the 2019 Match, you must take Step 2 CS by December 31, 2018. If you do not register now and schedule soon, it is possible that you will not be able to obtain a test date in 2018. At the time of this writing, the earliest available test date at any test center is in August 2018.

Link: April 2018 https://www.ecfmg.org/news/2018/04/09/imgs-participating-in-2019-match-should-apply-for-step-2-cs-now/

I plan to apply for matching in 2019, do I need to take the exam in December 2018?

- Sent through email

Hello,

Let me clear terminologies before I start explaining.

Match 2018 means: Application in September 2017, results in March 2018, Residency starts in July 2018.

You said apply for matching in 2019, which means apply in September 2019 for the March 2020 match, yes?

Let's talk about the 2019 match mentioned in the link you sent. It says currently, there will be no availability of testing centres for this year's match (September 2018 application, March 2019 Match, Residency starts in July 2019). The ECFMG website is able to predict the number of applications that they are going to receive. This year, they predict there will be no testing centers available, which is why I am guessing they are asking you to register in April (register now).

Your confusion arises because of two reasons:
You don't know the match terminologies with respect to the year.
You don't know the timeline for the match.

When they mean apply right now and give the exam before December, they are talking as a general mandatory requirement. IT IS A ABSOLUTE MUST HAVE.

To be a competitive candidate, IMGs tend to give the exam in such a way that the results are out before September so that we have all the exam results before the application cycle of the match. IT IS OPTIONAL BUT PREFERRED.

So really, the virtual deadline to give the exam for us is July. We also prefer to graduate before September to get ECFMG certified, however, it's not mandatory.

It is quite vigilant of you to keep an eye out for these notices on the ECFMG website.

Since the dates are not easily available, when you plan to go for an elective, try to register in advance.

If you go to the ECFMG website, there is a site called a step 2 CS scheduling and you can view the dates available at various centres. So register as soon as possible if you want to get your desired dates. Here's the link https://csess2.ecfmg.org/calendar.aspx

PS: The step 2 CS permit is available for one year and it does not expire quickly (compared to other exam permits that expire in 3 months) which is a huge advantage.

So to summarize, July is the ideal deadline for Step 2 CS to get results before September (Application submission). December is the mandatory deadline to get result before February (ROL submission, to be eligible for the match).

Google the step 2 CS reporting schedule to help plan for your match.
https://www.ecfmg.org/news/2018/04/18/results-reporting-schedule-for-step-2-cs/

Hope that helps!

-IkaN

Saturday, May 5, 2018

Enamel Rods


  • An enamel rod is the basic unit of tooth enamel. 
  • Measuring 4 μm wide to 8 μm high, 
  • An enamel rod is a tightly packed, highly organized mass of hydroxyapatite crystals
  • It provides rigidity to the rods and strengthens the enamel.
  • Enamel rods normally have a clear crystalline structure
  • Light can pass through rods
  • Many rods have a fish scale appearance
  • Shape: Hexagonal
  • Pattern: Keyhole or paddle-shaped prism pattern


Number: 

  • 5 million= mandibular lower incisor to
  • 12 million= maxillary first molar

The direction of rods:

  • Rods are rarely straight, they follow a wavy course from dentin to the enamel surface
  • Generally, they are oriented at the right angles to Dentin surface 
  • Horizontal direction in the cervical and central part of the Crown
  • Oblique to vertical direction in the incisal regions
Striations: 

  • Rods are built up of segments separated by Dark Line in a rhythmic manner
  • Visible by the action of mild acids
  • Striations are uniform of 4 centimetre
- Written by Anisha Valli


Hertwig's Epithelial Root Sheath- HERS


Hertwig's epithelial root sheath
  • It originates from the cervical portion of the enamel organ.
  • It plays an important role in determining shape length size and number of roots.
  • It is a double layer of cells which consists of outer enamel epithelium and inner enamel epithelium.
  • Root sheath extends around dental papilla and separates it from surrounding dental follicle all through except the Basil portion.
  • Inner enamel epithelial layer of root sheath influences the formation of odontoblast from the outer portion of the radicular dental papilla. 
  • These odontoblasts lead to the formation of the first layer of radicular dentin.

As the first layer of radicular dentin is laid down:
  • HERS loses its continuity 
  • The cells of the dental follicle or dental sac invade double layer of HERS 
  • Root sheath degenerates to form epithelial Islands

Therefore, it allows connective tissue of dental follicle to come in contact with newly formed radicular dentin. 

This causes differentiation of cementoblast from dental follicle which deposits cementum on newly formed radicular dentin.

Transitory Sutures

Transitory Sutures are found in cap stage of tooth development

Enamel Knot: Enamel organ cells form a knob-like extension which extends to the underlying dental papilla.

Enamel cord: it is a vertical extension of enamel knot

Enamel septum: when enamel cord extends to meet outer enamel epithelium it divides stellate reticulum into two parts

Enamel navel: Depression present at the junction of enamel septum and Outer enamel epithelium is known as enamel navel and it resembles umbilicus

Enamel Knot signals determine the shape of the tooth
Enamel Knot and Enamel cord act as a reservoir of dividing cells 

- Written By Anisha Valli

Wednesday, May 2, 2018

Human Papilloma Virus mnemonics

To remember that HPV vaccination starts at 11 years old and that HPV is the most common STD in the US, use the following mnemonics:

=> Write Human Papilloma Virus with 11 instead of the 2 Ls so it becomes as follows:
Human Papi11oma Virus

the 11 in papilloma will remind you of number 11 :)

=> remember HPV as the Highest Prevalent Virus :P
so this will remind you that it is the commonest STD

and that's it

-Murad

Tuesday, May 1, 2018

MDMA mnemonic

Hello! 

This post is about MDMA.

MDMA? Yep. It's short for 3,4-methylenedioxymethamphetamine.

Commonly called “Molly” or “ecstasy”.
MDMA can elicit feelings of euphoria, wakefulness, intimacy, and disinhibition.

Intoxication causes dangerous side effects such as:
Hypertension
Hyperthermia
Delirium
Psychomotor agitation
Hyponatremia
Intracranial hemorrhage
Myocardial infarction
Aortic dissection
Disseminated intravascular coagulation
Rhabdomyolysis
Seizures
Serotonin syndrome

Here's a mnemonic!



That's all!
-IkaN