Fish oil for treatment of asthma

Hello

Asthma is a chronic, exaggerated and allergic inflammatory response in the respiratory airways to certain allergens that vary according to seasons.

Omega- 3 fatty acids in high- quality fish oils and other products reduce the inflammation by regulating B- cell function. IgE production is reduced, which otherwise acts to cause asthma symptoms and allergic reactions in patients with mild form of asthma.

The fatty acids are used up by the cells in the lining of respiratory passages to produce hormones that tend to "turn- off" certain factors responsible for attracting white blood cells to the site of inflammation such as leukotrienes, interleukins, and other cytokines.

However, these oils are less effective in severe forms of the disease and in the majority of patients taking corticosteroids.

According to a study, prenatal exposure to fish oils (mainly in third trimester) reduces the risk of wheeze and asthma in children.


Thats all
- Jaskunwar Singh

Increased Intracranial pressure clinical features mnemonic

Increased intracranial pressure clinical features mnemonic- 5Ps

P- Persistent projectile vomiting (due to stimulation of CTZ)

P- Persistent headache (the patient presents it as the "worst" headache of his life)

P- Palsy (sixth nerve palsy and diplopia)

P- Papilledema (bilateral)

P- Personality disturbances (behavioral changes)

Thats all

- Jaskunwar Singh

Levels Of Prevention & Mode Of Intervention

Hi everyone,
this is notes on community medicine topic. levels of prevention and mode of intervention.
Hope it helps.
That's all
Shubham Patidar jmc 013

Vitamin D and multiple sclerosis

Hey awesomites!

Since I have written posts regarding the association of vitamin D deficiency with certain neurological disorders previously, I am here again with one more addition into the box (on sincere request of our main author IkaN.. :p ).

Crispy C.R.I.S.P.R.!

10 years ago,only a few would have thought that a device in our pockets would be good enough to access all the information of the world, would do social networking, calls, would calculate, act as a torch and what not. 

We today are on a similar brink ofrevolution in genetic engineering, where the effects would be so magnificent that they would need to be measured on a Richter scale! 

Enter CRISPR, which is an acronym for 'clustered regularly interspaced shortpalindromic repeats', a  crispy new technology which promises to shrink the costs involved in genetic engineering by 90%, makes the procedure easier andshorter.

*What is it? 
We have managed to hack an antibacteriophage mechanism in bacteria to our advantage. 

Only a few bacteria survive bacteriophage invasion. To protect themselves from a further invasion, they store a part of the phage DNA into their archives. 

When another attack does occur, an RNA copy of the archived phage DNA is presented to what is known as a CAS 9 protein.

CAS 9 compares the two copies, one from the foreign DNA and the other from the archives, and is very precise at that. 

If it finds a 100% match, it cuts off thenew phage's DNA, thus rendering the attack a big embarrassment for the bacteriophage. :-p 

*What can we do with it? 
Oh, a lot of awesome things! 

-Pissing off viruses
In 2015, scientists armed with CRISPR achieved a significant reduction of HIV load from patiens. 
This year, in mice, they slashed off 51% HIV DNA from mice, just by a couple of shots in their tails! 

*Making cancer re evaluate its careerchoice- 
Malignant cell detection by the immune system can be enhanced. 

*Designer babies- 
A lot of desirable traits- super awesome eyesight, superman esque strength and so on, can be selected from a wide palette during embryogenesis.

*Bidding adieu to genetic diseases

*Making ourselves look hot at 120-

CRISPR holds the potential to slow and even reverse ageing! We can take a leaf off the books of certain aquatic species who already are doing that. 

.. and a lot more. 

*The last word
A few controversies sorround though.
- We don't know if any adverse 
  reactions may triggered, as our 
  knowledge is still just the tip of the
  iceberg.
- Some powers like say dictators
   might use it to gain precedence.
- The fear of genetic pollution.

Anyway, these are just hurdles which we need to plan and overcome for a glorious future for humanity! 

Source- Kurzgesagt. 


  

Serological And Viral Markers Of Hepatitis B Infection Made Easy

Hello everyone
This is Shubham Patidar . Today I am posting my notes on Serological  and Viral Markers of Hepatitis B Infection  in concise and simple way. This is very important short note ask in pharmacology, pathology, community medicine, medicine , microbiology, in undergraduate theory exam . and mcq comes in post graduate medical examinations.
Enjoy Learning !
That's all !

Primary Health Care

Hey Awesomites

Today its a short post ( a mnemonic actually ;p )  on the principles and elements of primary health care. (I was asked in SPM viva a few days back. ;p )
As a rule, always find a mnemonic in the name itself, I took care of it and made it in the easiest way possible. So here it is ..

C- Community participation
A- Approach (multi- sectorial)
R- Right technology (appropriate)
E- Equitable distribution of health services.

Elements of primary health care: MI NEEDS
- MCH and family planning
- Immunization
- Nutrition
- Education
- Endemic and common diseases
- Drugs provision
- Sanitation.

Thats all
Happy Medicowesome :)

- Jaskunwar Singh

Pentavalent vaccines

Hey Awesomites!

Let's discuss something about the pentavalent vaccines and what advantage they have in the immunization of newborns..

The Sustainable Development Goals: Mnemonics and explanation

Hi everyone! I'm back with a note. This time on the Sustainable Development Goals (SDG's).

This is a crisp summary of what we need to know about them as Doctors or Health Care Practitioners (in any part of the world). They're so important that a major chunk of the Coldplay concert in Mumbai was based on them. (And every other person spoke about them. How Magic-al).

And they're Also very important for the Community Medicine students from India. So here goes :

SDG's were adopted by nations of the world on 25th September, 2015 to be achieved till 2030. 

They want to do 3 P's. 

End Poverty,
Bring Prosperity to all and
Protect the planet. 

A. The important Health related Goals : 

(Mnemonic by our IkaN)

pH HE EWE

(HE EWE as in Adam and Eve)

1 Poverty 

2 Hunger 

3 Health care 

4 Education 

5 Equality 

6 Water 

7 Energy 

B. Goal 3: Ensure Healthy lives and Promote Well Being. 

Targets 

Remember: BAMS VIP
Baby Adult Mother Sex. 
(OR : Adult and Mother have Sex to get Baby)
Vaccine. Infections. Pollution. 

Baby:
- Neonatal Mort - has 12 letters , so to be reduced to less than 12 by 2030. 

- Under 5 Mortality Rate  - 5*5 = 25. So less than 25 by 2030 

Adult:
- Decrease the burden of NCDs to one third of present.
- Mental health burden to be reduced. Tobacco control. 
- Drug abuse to be tackled. 

Mother:
- Maternal Mortality to less than 70 per 1 lakh world wide. 

Sex: 
- Sexual health and reproductive health strengthening. 

Vaccines:
- Promote and develop.

Infections:
- Tackle TB HIV Malaria Other tropical diseases Diarrheal diseases. 

Pollution:
- Air, Water, Soil, Noise pollution to be tackled. 

Kudos to IkaN who helped me out of this tough spot. This was a life saver and you're the best :* :)

Hope this helps everyone.
Until next time.

~A.P.Burkholderia

Descriptive Epidemiology

Hello everyone !
Here's a video telling you a little bit of the Descriptive Epidemiology.
Let me know how you like it and I can continue to make some more to finish it up and tell you more about Epidemics!

Cocaine in the brain - "The Addiction"

Hey Awesomites!

Here I will be talking about a social problem amongst the youngsters - “Addiction to cocaine”. 

Indices of obesity mnemonic

Hello!
Let's mnemonic-fy everything!

Zika virus infection and the Alzheimers'

Hello everyone!


The mosquito-borne zika virus has spread to most of the parts of Latin America, Pacific islands and the US. It has been recently linked to Alzheimers' disease and depression!

The IMNCI problem - Solved. (Mnemonic)

Hi everyone !
So I was just studying Pediatrics and sometimes they expect us to remember how to fill the IMNCI form 😭 #SoCruel.
So here's a mnemonic I made for the headers :

For a child below 2 months -->
Bl*w Job TDM

So
Bl*w= Bacterial infection
Job= Jaundice
T=Temperature (hypothermia)
D= Diarrhea
M= Malnutrition

__________________________________
For a child above 2 months -->
3 Di*ks in FEMAles Is Fun

So 3 D*cks are  :
Danger signs
Diarrhea
Dypnea /difficult breathing /cough.

FEMAles  :
  F = Fever
  E = Ear problem
  M = Malnutrition
  A = Anemia

Is = Immunization

Fun = Feeding .

Hope you find this one helpful.
Will continue with the GI hormone series once exams are done.  :p
Bye.

Antibodies to stop Heart disease!

Hello everyone!

Cardiovascular disease is one of the most leading causes of death in the world today, with major risk factors not merely high cholesterol and high blood pressure but also the actual lesions being directly responsible for the disease- Atherosclerotic plaques.
Antibodies that help the immune system remove dead and dying cells have been shown to reduce atherosclerosis. 
Read further to know the "how" of that.. :D

Strongyloides Stercaralis Notes And Mnemonics

Hey everyone!
These are microbiology  notes made by me =) Hope it helps you ☺

Immunization schedule notes and chart

Hello!
So in these notes, I write about type of vaccine, strain used for vaccine prepration, diluent, content, dose, route, site of vaccination,strength,  protective efficacy, protective duration, contraindications, complications, age limit and storage of vaccines and special points used in the Indian immunization schedule.

It's a nice summary for those studying pediatrics, preventive and social medicine, pharmacology, microbiology and medicine. 

Stay Awesome ☺

Olympics 2016 and the Zika

Hey Awesomites!!!

You all know the Olympics and Paralympics are on their way in August and September. Excited, aren't you? Woohhooooo! :D

Its taking place in Rio de Janeiro, Brazil this year. So if any of you or your known really plan to travel to Brazil for the Olympics and the Paralympics... You have to know about the current situation of Zika virus out there. Brazil, along with many surrounding countries of America, are experiencing an Outbreak of Zika Virus.

Biotin deficiency mnemonic

Hello!

Here's an interesting case of vitamin deficiency you should read.

Biotin deficiency is rare. Nice to know for exams though. Soooo.. I made a mnemonic. Biotin reminds me of the comic character, Tin Tin!

Biotin mnemonic

LDL Cholesterol- The 'bad' turns good

Hello!

Since long back, the low-density lipoproteins have been linked to high rates of cardiovascular disease and mortality! But is it really so?