Tuesday, October 24, 2023

Mnemonic for Ototoxic drugs

Some of the ototoxic drugs are presented to you here with a mnemonic 


Think about a situation when you got deaf due to some ototoxic drugs and now you go to a pandet named Adam for cure

So Pandet Adam is our mnemonic 

P = Propranolol, platins(cisplatin, carboplatin)

A = aminoglycosides

N = NSAIDs (ibuprofen, salicylate, indomethacin)

D = Diuretics (furosamide, ethacrynic acid, bumetanide)

E = eryhtromycin 

T = tobacco 

A = Alcohol

D = defroxamide 

A = ampicllin 

M = anti Malarial (quinine, chloroquine, hydroxychloroquine)


And that's it. 

I hope it works for you all

InShaAllah!

Thank you❤

Monday, October 23, 2023

Perinatal Causes of Hearing loss | Mnemonic

 Imagine a situation in which an immature baby is to be born to a mother, so baby will be of low birth weight, and since there is birth going on early so there maybe a problem of anoxia due to prolonged labour, in this situation obstetrician will try to operate and get baby out quickly, so a chance of birth injury is there, birth injury may lead to meningitis, that may end up in sepsis, and for that we will need drugs and admission in NICU to handle the situation. 

So after keeping this type of perinatal situation in mind, you can keep some of the preniatal causes of heading loss 

  1. Immaturity and low birth weight
  2. Anoxic
  3. Birth injury
  4. Neonatal meningitis 
  5. Sepsis
  6. Time spent in NICU
  7. Ototoxic drug
  8. Neonatal jaundice (not in the mnemonic)
I hope it works for you all again like always
InShaAllah!
Thank you ❤

Mnemonic | Average Hearing loss in Different Ear lesions

The mnemonic was quite difficult in its genesis. 

But here it is:

Complete obstruction of Ear canal = 3ar (flip the E to 3) = 30dB loss

Perforation of tympanic membrane = perFORation = 40 = 10 - 40dB

Malleolar fixation = malle01ar = 10 = 10 - 25dB

Ossicular interruption with intact drum = 54dB (couldn't make for it ๐Ÿฅฒ)

Ossicular interruption with perforated drum = among all numbers from 1 - 10 which digit is most perforated? ( I mean having more holes)
The answer is 8 and vertical half of 8 is 3 so 38dB

Closure of oval Window = thats the last resort of conductive hearing loss and max hearing loss possible in conductive hearing loss is 60dB never above it. So no mnemonic for it. 


If you have any better than this pet me know in the comments 
I hope it works for you
In Sha Allah!
Thank you❤

Sunday, October 22, 2023

Mnemonic | Congenital and Acquired causes of Conductive hearing loss

Some of the causes of Congenital and acquired conductive hearing loss can be remembered with this mnemonic

Think about a Calf being given birth by (obviously๐Ÿ˜‚) a cow. So she just got mom for the first time (ft)  

So here it is the mnemonic just heard
Congenital causes of conductive hearing loss

CAlF:

C = Cholesteatoma
A = Atresia ( of meatus )
l...........................
F = fixation of malleable head, footplate of stapes a ossivular discontinuity 

Now the Acquired causes of conductive hearing loss

MOM FT.
M = Membrane (tympanic) perforation 
O = ossicles fixation or discontinuity 
M = Mass in middle ear
F = Fluid in the middle ear
T = Tubal Blockage ( eustachian tube )

You can add in them further the examples in the causes I listed here. 
I hope it works again for you people
In Sha Allah!
Thank you๐Ÿ‘ป

Morphology of Rapidly progressive glomerulonephritis

The morphology of crescentic glomerulonephritis seen in rapidly progressive glomerulonephritis (RPGN) is quite easy, so here i am just sharing the difference between differences in the types of RPGN only:


Points of difference

Immune complex mediated

Anti GBM antibody mediated

Pauci immune type

Endocapillary proliferation

      รผ

              รป

               รป

Mesangial proliferation

       รผ

            

 

 

Immunofluorescence

Linear staining

       รป

              รผ

               รป

Granular staining

       รผ

              รป

               รป

Dense immune complex deposits

       รผ

              รป

               รป



I hope it will help you in remembering the morphology 

In Sha Allah

see you soon with something new again IA

Thank you ๐Ÿ˜Š

Thursday, October 19, 2023

Mnemonic | Morphology of IgA nephropathy

 Morphology of IgA nephropathy will be derived from its pathogenesis and the disease name.


so the mnemonic is presented here:

Pathogenesis = indicates about role of immunoglobulins and mesangial cells

now about these 2 things take the name of the disease:

IgA = A = All 

= all main antibodies in infections (IgA, IgG, IgM) 

= all mainly possible mesangial morphologies ranging from mesangial widening, diffuse mesangial proliferation endocapillary proliferation, segmental sclerosis, , to crescentic glomerulonephritis  


(remember it by keeping in mind the structure of glomerulus in which from center to periphery comes mycangium, capillaries and then epithelium of glomerulus)


I hope it works for you all again ๐Ÿ‘ฝ

In Sha Allah!

Thank you ๐Ÿ’“

Wednesday, October 18, 2023

Mnemonic | Uncinate Herniation / Transtentorial Herniation

The word that comes first in my mind when i see uncinate written in the book is UNCLE

I don't know why but this is what it is!

so my UnKle is PHD

U = uncinate herniation

K = Kernohan's Notch 

P = posterior cerebral artery compression

H = hemiparesis (ipsilateral)

D  = Duret hemorrhage (midbrain and pons)


  • and from posterior cerebral artery point and hemiparesis, another thing can be linked which is CN# 3 paralysis

because posterior cerebral artery supply mainly occipital lobe so some problem with eye may occur which is actually related to oculomotor nerve compression (just a linker not the actual pathophysiology)


I hope it works for you all again!

In Sha Allah!

Thank you ๐Ÿ’“

Mnemonic | Morphology of Membranoproliferative Glomerulonephritis

Here again I am back with another mnemonic to remember the morphology of Membranoproliferative Glomerulonephritis 

Pathology is fun ๐Ÿ˜ญ๐Ÿ˜‚

I hope the feelings are obvious to everyone now lol ๐Ÿ˜


this mnemonic will be mainly derived from the name of the disease:

Membrano proliferative Glomerulonephritis:

  • if I abbreviate this disease to MG (membranoproliferative glomerulonephritis), than i can make you remebr that MG is a car manufacturing company so its cars would make a tram track appearance on roads when they are driven

and then comes the breakdown of the disease name:

  • Membrano = meaning something wrong is with basement membrane of glomerular capillaries

tram track appearance 


  • Proliferative  = meaning something is proliferating 

so endothelium, mesangium is proliferating (ME from membrano)


  • Glomerulonephritis = inflammation indicates infiltration of leukocytes as it is a nephritic syndrome mainly


specific types of Membranoproliferative glomerulonephritis have these all above said features but certain differences which are mentioned in this table below:

Differences

Membranoproliferative glomerulonephritis type 1

 

Membranoproliferative glomerulonephritis type 2

(C3 glomerulopathy)

Dense deposit disease

C3 deposits

 

Deposited in irregular pattern

(subendothelial ONLY)

 

 

Waxy deposits

(mesangial, subendothelial and tubular BM)

 

Ribbon like highly dense deposits

(mesangial, subendothelial and tubular BM)

Classic complement system components

 

Present

 

Absent

 

Absent


I hope this was fun also for you like always!

I hope it works you again

In Sha Allah!

Thank you ๐Ÿ’“

feel free to ask any study related question in the comment section๐Ÿ‘ฝ

Tuesday, October 17, 2023

Mnemonic | Morphology of Membranous Nephropathy |

Morphologies are always very difficult, atleast for me and my colleagues ๐Ÿ˜ฅ

so I have made a mnemonic for the membranous nephropathy morphology:
I will try to keep it simple and make the name of the disease a major hint for the morphology:

4 things will get evident from the name of the disease:

1.  Word membranous indicates towards basement membrane of capillaries of glomerulus, and what can happen to it in inflammation or disease?
mostly thickening of basement membrane of capillaries

2.  M stands for Mehrab (the place where Muslim religious leader of stands to lead the prayer) - picture is shown below

   
took this image from alamy website (and these pictures are downloadable from there without any consent)

so the leader stands in it and it appears like dome if seen from outside = dome and spike pattern 

3.   next comes the dome again,  as I described the dome appearance from outside of this mehrab so if I imagine that dome being the outside of capillaries which will blink in mind the point of 
sub epithelial deposits 
(as epithelium is on the outside of capillaries in glomerulus)
   
4.  remaining morphology is same as in other nephrotic syndromes (effacement of podocytes, etc.)



I know it has got long but to remember morphologies and then forgetting is worst than understanding this mnemonic and keeping the memory long enough atleast till final exam. lol ๐Ÿ˜‚

I hope it works again for you like my other mnemonics
In Sha Allah!
Thank you ๐Ÿ’“












Monday, October 16, 2023

Roll over phenomenon | A kind of Mnemonic |

Roll over phenomenon is even though simple thing but still a good memory anchor would be beneficial in future.

so here it is a mnemonic for how to remember roll over phenomenon


what does the word indicate from roll over?

 it means roll over something or like that meaning 

now look at the picture of its graph, it also shows like as if it just rolled up the hill and then over it and then rolled down the hill  like a car. lol


so that is it, the roll over phenomenon, meaning sound intensity is best heard at the peak of the mountain and it decreases on either side of the rolled over mountain.


i hope your brain keep this anchor with it for your life long

In Sha Allah

Thank you

Saturday, October 14, 2023

Mnemonic for Incubation Period of Dengue virus

Incubation period of dengue virus is 3-10 days

How to remember this with all so many incubation periods in community medicine?๐Ÿ˜ข


so the solution is in its name:


DENgue

so DEN rhymes with ten 

and look at the E in it, flip it and you get 3

so 3-10 days


and that's it ๐Ÿ™ˆ 

I hope it works for you 
In Sha Allah !
Thank you ๐Ÿ’“

Allah Hafiz!

Mnemonic for Morphology of Focal Segmental Glomerulonephritis

 Morphology of Focal segmental glomerulonephritis is derived mostly from its name and its pathophysiology.

so here it is:๐Ÿ˜

1st word = Focal = only some glomeruli are involved (mainly juxtamedullary)

but it can extent later to whole of cortex as well

2nd word = segmental = only a portion of glomerulus is involved

but later may extend to whole of glomerulus which may extend into interstitium and ultimately tubular atrophy can occur

3rd word = glomerulosclerosis = scarring/fibrosis of glomerulus

scarring hints scarring obviously (fibrosis I mean)

and scarring links to capillary lumen obliteration of glomerulus 

(imagine a situation when glomerulus will be sclerosed, it will get contracted and so capillary lumen will also start collapsing) - now link obliteration of capillary lumen with increased mesangial matrix

for this see the diagram of glomerulus and understand that mesangial growth can also compress upon the capillary lumen and cause lumen obliteration


Pathophysiology:

link the morphology with pathophysiology if you are reading pathophysiology of FSGS from Robbins pathology then it has said that some people think that FSGS is a derivative of minimal change disease and the hall mark of minimal change disease is 

EFFACEMENT OF PODOCYTES - SO this morphology is also here

and this effacement means leakage of plasma contents seen in minimal change disease that is proteins and lipids so here we see 

HYALINOSIS AND LIPID LADEN MACROPHAGES


I HOPE IT WORKS WELL.๐Ÿ‘€

In Sha Allah!


Monday, October 9, 2023

Mnemonic for causitive agents of Acute Postinfectious glomerulonephritis

How to remember that which organisms can be the cause of postinfectious glomerulonephritis?

Sometimes it gets very problematic, not because that is important to know, but because sometimes you just want to remember everything  from ROBINS PATHOLOGY. lol
so here it is:

BACTERIAL CAUSES:


Post infectious glomerulonephritis is also called post streptococcal glomerulonephritis and it is a quite obvious things. From this we have:
                                                                    PostSTreptococcal
the name itself indicates Streptococcus
P indicates Pneumococcus and ST for Staphylococcus 


VIRAL CAUSES:

From the name of post streptococcal glomerulonephritis, the first thing that comes to mind is some relation with children because when we studied these topics in our immunology chapters than glomerulonephritis and post infectious endocarditis were written next to each other. so children picture is now clear in our little brains, now what children do most of the time? CRY! lol And how:

MM AHu ahu....................................................aaaaaaaaaaaaaaaaaaaaaaaaaaaaa lol and mother says CHHHHH tos top him from crying (or may even slap - a vicous cycle may begin or terminate. you can relate yourself. lol - sorry for your nostalgia!)

M = mumps
M = measles
A = aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa (thats nothing. lol)
H = HBV HCV
CHHH = chickenpox

and that's it! 
I hope it works for you 
In Sha Allah !
Thank you ๐Ÿ’“