Autonomic hyperactivity (Mild hypertension, dry mouth)
Racing heart (Tachycardia)
Injection (Scleral, conjunctival injection)
Judgement impaired
Uphoria (Euphoria)
Anxiety
Nystagmus
Ataxia
The crown rump length in mm is calculated by subtracting 42 from the gestational age in number of days.
The gestational sac diameter in mm is calculated by subtracting 30 from the gestational age in number of days.
Patient is in a panic attack:
Use benzodiazepines because they act fast.
Long term treatment for panic disorder:
SSRIs
Long term treatment for GAD:
SSRIs
Buspirone
A schizophrenic presents with galactorrhea. The patient’s medication regimen includes haloperidol. Blockade of which neurotransmitters is responsible for this patient's clinical presentation?
Dopamine. Since it is a Prolactin Inhibitor - Inhibition of Dopamine causes hyperprolatctinemia.
Doubt: Level of dopamine also decreases in Parkinson's disease. So can hyperprolactinemia also be seen in Parkinson's disease?
In Parkinson's, there is loss of dopamine only in the substantia niagra.
There are 4 main dopaminergic pathways in the CNS:
1. Nigrostrial pathway which is involved in Parkinson's disease.
2. Mesolimbic pathway involved in Schizophrenia.
3. Paraventricular pathway involved in satiety.
4. Tuberoinfundibular pathway involved in prolactin secretion.
Drugs can affect all pathways, that's why, the side effects. But Parkinson's only hits the nigrostrial pathway.